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MEDICAL ANIMATION TRANSCRIPT: Drug metabolism is the chemical conversion of drugs into water soluble compounds that can be excreted by the body. Drug metabolism mainly takes place in the liver, while excretion mainly takes place in the kidneys. Following drug administration, drugs must pass through tightly packed cells, crossing cell membranes to reach their sites of action. Usually drugs are lipophilic or fat soluble compounds, and cell membranes are composed of phospholipids, so drugs are able to cross them. However, for excretion by the kidneys, it's necessary to convert drugs to water soluble or hydrophilic compounds. Drugs are usually administered orally or parenterally. Parenteral drugs bypass the digestive tract. Parental routes include injection, transdermal patches, lotions, inhalants, and suppositories. If injected, the drugs reach general circulation quickly and have an immediate effect. If taken orally, drugs must pass through the cells of the gastrointestinal tract. Drugs cross through cells of the GI tract and travel to the liver via the hepatic portal vein. The liver has a chance to metabolize some of the drug before it goes into general circulation, this is called the first pass effect. In the liver, drugs enter hepatic cells where a series of enzymes in smooth endoplasmic reticulum metabolize them. Drugs move through the phospholipid membrane of endoplasmic reticulum. Hepatic microsomal enzymes such as p450 convert drugs from lipophilic to hydrophilic compounds. Repeated use of certain drugs increases the amount of metabolic enzymes and increases drug metabolism. This is called enzyme induction. Conversely, certain drugs compete to bind to metabolic enzymes thereby decreasing drug metabolism. This is called enzyme inhibition. Once metabolized, these hydrophilic metabolites leave the cell ready for excretion by the kidney. A drug's duration and intensity of effect are largely determined by metabolic rate. Increased metabolic rate will decrease drug duration and intensity by facilitating excretion. Decreased metabolic rate increases drug duration and intensity. A few of the factors affecting metabolic rate are the first pass effect, liver disease such as cirrhosis, neonates in the elderly have decreased liver function, compromised blood flow to the liver will lower metabolic rate, variation in amount and type of hepatic enzymes, poor diet and nutrition can affect normal liver function, and higher circulating drug levels due to dosage or patient's weight take longer to metabolize. ♪ [music] ♪<br/>
⏲ 1:42 👁 10K
video canvert to audio offline procces<br/>video convert to audio offline procces ||NO APPS NO WEBSITE ||How to convert Video to MP3offline procces ||NO APPS NO WEBSITE ||<br/>#convert #videotoaudio #mp4tomp3 <br/><br/><br/><br/>video convert to audio<br/>video convert to audio mp4<br/>video convert to audio app<br/>video convert to audio apk<br/>video convert to audio app free download<br/>video convert to audio software free download<br/>how to transform video into audio<br/>how to translate video audio<br/>how to convert audio to video free<br/>video converter to audio file<br/>video convert to audio online<br/>video convert to audio iphone<br/>instagram video convert to audio<br/>facebook video convert to audio<br/>tiktok video convert to audio<br/>video converter to audio app download<br/>video converter to audio apk download<br/>convert video to audio android<br/>convert video to audio android online<br/>convert video to audio ai<br/>convert video to audio audacity<br/>convert video to audio apk mod<br/>how to convert a video to audio only<br/>how to convert a video to audio file<br/>how do i convert a video to audio<br/>how do i convert a video to an audio file<br/>convert video to audio by url<br/>convert video to audio by vlc<br/>convert video to audio telegram bot<br/>best video convert to audio app<br/>best video convert to audio<br/>convert audio to blank video<br/>batch convert video to audio<br/>convert youtube video to audio book<br/>best software to convert video to audio<br/>best way to convert video to audio<br/>how do i convert video to audio<br/>audio video conversion<br/>can i convert a video to audio<br/>convert video to audio capcut<br/>convert video to audio canva<br/>convert video to audio clip<br/>convert video to audio clideo<br/>video change audio codec<br/>how to convert video to audio chromebook<br/>video to audio converter cutter online<br/>convert youtube video to audio cd<br/>can i convert video to audio on iphone<br/>can vlc convert video to audio<br/>convert video to audio windows 10<br/>convert video to audio windows<br/>convert video to an audio file<br/>convert video to audio vlc<br/>convert video to audio free<br/>video converter to audio download app<br/><br/><br/>Disclaimer Disclaimer- Some contents are used for educational purposes under fair use. Copyright Disclaimer Under Section 107 of the Copyright Act 1976, allowance is made for \
⏲ 3:20 👁 10K
Dive into the world of XLSM files, where dynamic content and macros collaborate to breathe life into Excel workbooks. However, when the need arises to share or present your data comprehensively, the universal allure of the PDF format becomes evident. This video shows you how to seamlessly convert XLSM files to PDF using Visual Paradigm Online. Whether you are a finance maestro maneuvering intricate financial models or a student orchestrating data-centric projects, VP Online guarantees a friction
⏲ 40 sec ✓ 28-Dec-2023
#lakhwinderwadalilive #lakhwinderwadali #wadalibrothers<br/>#tumaneyanamane #lakhwinderwadali #wadalibrothers <br/><br/>Tu Mane Ya Na Mane – Live in the soulful voice of Lakhwinder Wadali Ji <br/><br/>➟ Event: HT City Friday Jam Season 8 <br/>➟ Venue: DLF Cyberhub, Gurugram <br/>➟ Event Date: 13 October, 2023 <br/>➟ Special Thanks: Music Director Aar Bee. <br/>➟ Event By: Hindustan Times <br/>➟ Sponsored By: Hero, Pass Pass, Cantabil <br/><br/>LAKHWINDER WADALI <br/>Lakhwinder Wadali Born in Guru ki Wadali village of Amritsar (Punjab), Lakhwinder Wadali belongs to the Wadali family (Wadali Brothers) of Patiala Gharana, Punjab. He trained extensively in the art of singing folk music under the guidance of his father Padma Shri Ustad Puran Chand Wadali Ji and uncle Ustad Shri Piyare Lal Wadali Ji (Well Known As Wadali Brothers). Among the leading folk and Sufi singers of his generation, Lakhwinder Wadali has evolved an individual style in his presentation and has gained wide popularity. His style of singing combines a fine blend of classical and contemporary music. Alaaps and Taans are the vital aspects of his music. <br/><br/>He has performed with many eminent musicians such as Himesh Reshamia, Rahat Fateh Ali Khan, Shanker Mahadevan, Mikka Singh, Shan, Shreya Ghoushal, Ila Arun, Anand Raj Anand and Mohit Chauhan. Lakhwinder Wadali has performed widely in the country and abroad. The foremost exponents of Punjabi Sufiana qalam, Lakhwinder Wadali Ji, have a diverse repertoire and excel in singing Sufiana qalaam by Baba Bulleh Shah, Shah Hussain, Baba Farid, Guru Nanak Dev Ji and Sultan Bahu. The rich gayaki of the Patiala gharana is evident in their soulful singing. For his dedicated work in preserving and promoting Punjabi folk music. <br/><br/>Lakhwinder Wadali Ji has been honoured with several awards including the PTC Channel Punjabi Music Award for “Best Debut Album” by PTC Channel Punjabi (2005), the “Best Sufi Singer of India” conferred by Watno Dur Channel in Toronto, Canada (2005), the PTC Channel Punjabi Music Award for “Best Sufi Song” awarded by PTC Channel Punjabi (2007), the Best Singer Award given by Canadian Government in Toronto, Canada (2009), and the Hamdard Award (2013). <br/><br/>Lakhwinder Wadali Ji is awarded the Ustad Bismillah Khan Yuva Puraskar of Sangeet Natak Akademi (Ministry Of Culture, Govt. Of India) for the year 2012 for his notable talent in the field of folk music of Punjab. <br/><br/>#lakhwinderwadalilive #lakhwinderwadali #wadalibrothers
⏲ 18:56 👁 100K
# VLOG 1<br/>IN THIS VIDEO WE WILL LEARNHOW TO EXCHANGE MONEY IN BAKU AZERBAIJAN <br/>Azerbaijan Manat (AZN) exchange rates<br/>- 1 AZN = 163.59431 Pakistani Rupees (PKR)<br/>- 1 AZN = 0.587880 US Dollars (USD)<br/>- 1 AZN = 0.0527 Turkish lira<br/>- 1 AZN = 0.0187 Russian ruble<br/>- 1 AZN = 1.8497 euro<br/>Additional information<br/>- The currency code for Azerbaijan Manats is AZN<br/>- The currency symbol is ₼<br/>- The most popular Azerbaijan Manat exchange rate is the AZN to USD rate<br/>- The Xe Rate Alerts will let you know when the rate you need is triggered on your selected currency pairs<br/><br/>Please note that exchange rates are in constant flux and may have changed since the last update.
⏲ 3:33 👁 35K
XLSB files, the binary format of Excel workbooks, serve as repositories for your data-driven endeavors. However, when the time comes to share, distribute, or archive your spreadsheet information, the versatile PDF format emerges as the go-to solution. In this instructional video as we guide you through the seamless process of converting your XLSB files to PDF using Visual Paradigm Online. Whether you're a data analyst, business professional, or student managing spreadsheets, VP Online can help y
⏲ 40 sec ✓ 28-Dec-2023
Tom's Guide looks at if the Apple Watch the ultimate travel companion? From navigating on Apple Map directions and Siri translations to currency conversions, Apple Pay, and more. Even the benefit of the Apple Watch Low Power Mode for the 14-hour flight from New York City halfway across the world. In this week-in-the-life video, Kate covers all the best Apple Watch features and tips for travel, and even makes a few adorable friends along the way.
⏲ 8:25 👁 30K
Agenda of the Video▶️: To Share the Steps, How-To Edit and Publish in Excel to Update Data in Dynamics 365 Business Central (D365BC).<br/><br/>Hint: Use \
⏲ 4:59 👁 20K
Excel workbooks are formidable tools, but XLTM files elevate it with their macro-enabled prowess. Unlike standard XLSX files, XLTM (XML-enabled Macro-Enabled Template) extends the functionality by incorporating macros, enabling automation and dynamic data manipulation within the Excel environment. The inclusion of macros equips users to automate repetitive tasks, execute complex calculations, and infuse interactivity into their spreadsheets. XLTM, with its macro capabilities, serves as a versati
⏲ 40 sec ✓ 28-Dec-2023
Corolla conversion<br/>
⏲ 0:20 👁 5K
Do you like vanlife? Subscribe to our channel and follow all the latest news about nomadic life on <br/>https://www.vantour.net<br/>Follow vantour on social media <br/>Instagram: https://www.instagram.com/the.van.tour/<br/>Twitter: https://twitter.com/vantour_<br/>Pinterest: https://www.pinterest.com/thevantour/<br/>Tiktok: https://www.tiktok.com/@van.tour<br/>SnapChat: https://www.snapchat.com/add/van.tour<br/>Facebook: https://www.facebook.com/the.van.tour
⏲ 0:11 👁 5K
Student all work in.office
⏲ 2:50 👁 5K
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